Review: the Rh blood group D antigen ...dominant, diverse, and difficult

The Rh blood group system: a review

The Rh blood group system is one of the most polymorphic and immunogenic systems known in humans. In the past decade, intense investigation has yielded considerable knowledge of the molecular background of this system. The genes encoding 2 distinct Rh proteins that carry C or c together with either E or e antigens, and the D antigen, have been cloned, and the molecular bases of many of the anti...

THE Rh BLOOD GROUP SYSTEM

T he Rh blood group system is one of the most polymorphic and antigenic blood group systems. It is second only to ABO in importance in blood transfusion and is well known as a primary cause of hemolytic disease of the fetus and newborn (HDFN). The principal antigen is D, and the terms Rh positive and Rh negative refer to the presence or absence of D antigen. Caucasians of European extraction ha...

Rh and LW blood group antigens

History and nomenclature The Rh system is second only to the ABO system in importance in transfusion medicine because Rh antigens, especially D, are highly immunogenic and cause hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs). HDFN was first described by a French midwife in 1609 in a set of twins, one of whom was hydropic and stillborn, whereas the o...

Frequency of ABO and Rh (D) Blood Groups Among Blood Donors in Lahore, Pakistan

The clinical significance of ABO and Rhesus blood group systems has been well documented. The objective of this study was to determine the frequency of ABO and Rhesus blood groups in blood donors in Lahore, Pakistan, with a view to generate data with multipurpose future practicalities in the field of medicine. Blood groups of 3000 blood donors were determined by commercially available standard ...

ASSOCIATION OF ABO AND Rh(D) BLOOD GROUPS WITH TRICHURIASIS IN THE NORTH OF IRAN